张文姝

女，1993年5月出生，博士研究生，讲师。2022年毕业于东北大学分析化学专业，博士期间从事微流控、表面增强拉曼光谱在生物医学领域的应用研究。2022年加入中国消防救援学院，主讲无机化学、有机化学、普通化学，2023年获学院青教赛三等奖，带领学员参加全国大学生化学实验创新设计大赛、北京市大学生化学实验竞赛并多次获奖。

学术成果：

1、Wen-Shu Zhang, Xiao-Peng Liu, Shuai Yue, Ya-Ning Wang, Yue Wang, Zhang-Run Xu*. In-situ and amplification-free imaging of hERG ion channels at single-cell level using a unique core-molecule-shell-secondary antibody SERS nanoprobe. Talanta, 2023, 253: 123900.

2、Wen-Shu Zhang, Ya-Ning Wang, Zhang-Run Xu*. High sensitivity and non-background SERS detection of endogenous hydrogen sulfide in living cells using core-shell nanoparticles. Analytica Chimica Acta, 2020, 1094: 106-112.

3、Wen-Shu Zhang, Ya-Ning Wang, Yue Wang, Zhang-Run Xu*. Highly reproducible and fast detection of 6-thioguanine in human serum using a droplet-based microfluidic SERS system. Sensors and Actuators B: Chemical, 2019, 283: 532-537.

4、Xiao-Peng Liu, Wen-Shu Zhang, Jia-Hui Gu, Jie Wang, Yue Wang, Zhang-Run Xu*. Single-cell SERS imaging of dual cell membrane receptors expression influenced by extracellular matrix stiffness. Journal of Colloid and Interface Science, 2024, 668: 335-342.

5、Xiao-Peng Liu, Wen-Shu Zhang, Ya-Ning Wang, Wen-Qi Ye, Zhang-Run Xu*. In situ monitoring PUVA therapy by using a cell-array chip-based SERS platform. Analytica Chimica Acta, 2022,1189: 339224.

6、Xiao-Peng Liu, Jie Wang, Wen-Shu Zhang, Zi-Ling Ding, Jia-Hui Gu, Yue Wang, Zhang-Run Xu*. In-situ SERS monitoring of membrane receptor PTK7 for assessing cancer cell migration at single-cell level on a microfluidic chip. Sensors and Actuators B: Chemical, 2024, 404: 135298.

7、Ya-Ning Wang, Dan Song, Wen-Shu Zhang, Zhang-Run Xu*. Enhanced chemodynamic therapy at weak acidic pH based on g-C₃N₄-supported hemin/Au nanoplatform and cell apoptosis monitoring during treatment, Colloids and Surfaces B: Biointerfaces, 2021, 197:111437-111445. 

8、Ya-Ning Wang, Ying Zhang, Wen-Shu Zhang, Zhang-Run Xu*, A SERS substrate of mesoporous g-C₃N₄ embedded with in situ grown gold nanoparticles for sensitive detection of 6-thioguanine, Sensors and Actuators B: Chemical, 2018, 260: 400-407.